Volume 13, Issue 4 (Nov 2025)
Res Mol Med (RMM) 2025, 13(4): 0-0 |
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Asadian L, Hedayati N, Jafari S M A, Yazdian-Robati R. Aptamers as Targeting Agents: Revolutionizing the Delivery of Plant Bioactive Compounds for Cancer Treatment. Res Mol Med (RMM) 2025; 13 (4)
URL: http://rmm.mazums.ac.ir/article-1-642-en.html
URL: http://rmm.mazums.ac.ir/article-1-642-en.html
1- Assistant Professor of Emergency Medicine, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
2- Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
3- School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
4- Pharmaceutical Sciences Research Center, Institute of Herbal Medicines and Metabolic Disorders, Mazandaran University of Medical Sciences, Sari, Iran ,yazdianr921@gmail.com
2- Department of Pharmacodynamics and Toxicology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
3- School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
4- Pharmaceutical Sciences Research Center, Institute of Herbal Medicines and Metabolic Disorders, Mazandaran University of Medical Sciences, Sari, Iran ,
Abstract: (28 Views)
Cancer represents a significant public health challenge, being one of the leading causes of illness and death globally. The urgent need for innovative, effective, and less toxic therapeutic strategies is paramount. Natural products, particularly plant bioactive compounds, have shown notable anticancer properties but face challenges, such as poor solubility and low bioavailability. This review explores the innovative role of aptamers in enhancing the delivery of these compounds. Aptamers, with their unique properties, offer a promising solution to the challenges faced by natural compounds, facilitating targeted drug delivery and improving therapeutic outcomes. By leveraging the specificity and binding affinity of aptamers, we can revolutionize the delivery of plant bioactive compounds, ultimately advancing cancer treatment and improving patient care. The integration of nanotechnology further enhances the potential of aptamer-guided delivery systems, marking a significant advancement in cancer therapy.
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