Volume 5, Issue 4 (Nov 2017)                   Res Mol Med (RMM) 2017, 5(4): 61-68 | Back to browse issues page

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Bakhti M, Haghshenas M, Valadan R, Rabie Rudsari M. The Prevalence of HBV and HCV Infection in HIV Positive Patients in North of Iran. Res Mol Med (RMM). 2017; 5 (4) :61-68
Abstract:   (1864 Views)
Background: HIV infected persons are also at risk for Infection with other pathogens, like Hepatitis B virus (HBV) and Hepatitis C virus (HCV). One of the main steps in the planning of treatment and prevention is the study of the HIV positive population who have HBV and/or HCV infection.
The objective of this study was to determine the prevalence of HIV and Hepatitis B and C dual infection in north of Iran
Materials and methods: Blood samples were collected into EDTA containing tubes by sterile syringes and needles from 83 HIV positive patients which were previously confirmed by Real-time Polymerase chain reaction in the HIV center of the north of IRAN. A structured questionnaire was used to obtain socio-demographic data from participants. Samples were screened for Hepatitis B surface antigen (HBsAg) and anti-HCV antibody. All non-reactive samples were recorded as negative.
Results: Out of the 83 patients, 50(60%) were male and 33 (40%) were female. Positive hepatitis C antibody was found in 28 (33%) and positive hepatitis B surface antigen was present in 15 (18%) of patients. The frequency of all these three viruses co-infection was 7 (8%).
Conclusion: Seroprevalence of HCV and HIV co-infection was high and it was strongly related to mutual ways of acquisition.
Full-Text [PDF 347 kb]   (480 Downloads)    
Type of Study: Research | Subject: Medical Virology
Received: 2017/12/17 | Accepted: 2018/02/14 | Published: 2018/02/14

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