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Shahraki O, Daneshmand S. Solid Lipid Nanoparticles as an Efficient Delivery System for Natural Skin Care Cosmetics: A Review. Res Mol Med (RMM) 2023; 11 (1) :27-36
URL: http://rmm.mazums.ac.ir/article-1-524-fa.html

Background: Natural skin care products, as health & beauty products, have formulations derived from natural active ingredients. Cosmetic actives have been incorporated into their novel formulations such as sunscreens and anti-aging products, but the challenges associated with their low solubility, low penetration, and physicochemical instability upon dermal application remain unresolved. To overcome these limitations, one method is to use lipid-based carriers, which have been recognized for their crucial role in enhancing their low solubility, increasing skin permeation, and enhancing steadiness. This review study focuses on current advancements in skin care formulations that employ a new nanotechnology-based system consisting of solid lipid nanoparticles (SLNs).

Materials and Methods: In this review, we mentioned some experiments that have investigated the dermal applications of some natural products incorporated in SLNs formulation and discussed moisturizing, wound healing, sun protection, whitening and anti-tyrosinase, anti-aging and anti-acne activities.
Conclusion: The nanoparticles such as SLNs are used to effectively deliver cosmeceuticals and enhance the efficiency of skin care products.