COPE
Volume 9, Issue 1 (Feb 2021)                   Res Mol Med (RMM) 2021, 9(1): 0-0 | Back to browse issues page

XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ghazaei C. Effect of Rhamnolipids on Pathogenicity Characteristics of Microorganisms in Organic Compost. Res Mol Med (RMM). 2021; 9 (1)
URL: http://rmm.mazums.ac.ir/article-1-390-en.html
Department of Microbiology, University of Mohaghegh Ardabili, Ardabil, Iran , ciamakghazaei@yahoo.com
Abstract:   (91 Views)
Backgrounds: Rhamnolipids are hydrophilic glycolipids, often classified as biosurfactants and are produced by different bacterial species. Rhamnolipids are extensively studied in biological research because of their interesting features like antimicrobial, anti-fungal, and anti-viral activity.
Material and Methods: To study the antimicrobial effect of rhamnolipid a cross-sectional study was conducted (from November 2019 to June 2020) on the eight different pathogenic bacterial strains. These bacterial strains were isolated from the organic compost. Both, disc diffusion and broth microdilution methods, were used to evaluate the inhibitory effects of rhamnolipids on these pathogenic bacteria. Also protease and amylase enzyme activity was evaluated in these eight bacterial isolates.
Results: For Bacillus stearothermophilus, within the area of 31.5 mm no growth was observed, hence proving the inhibitory effect of rhamnolipid. The minimum inhibitory (MIC) and minimum lethal concentrations (MLC) were calculated for each bacterial strain and it has been found that the bacteria were more susceptible to rhamnolipids than most of the antibiotics. Strains were also quantified for their enzymatic activity of proteases and amylases. The bacterial strains like; Bacillus stearothermophilus, Brevibacillus brevis, Bacillus licheniformis and Bordetella petrii showed maximum protease activity. Whereas, other strains Escherichia coli, Enterococcus faecalis, Enterobacter aerogenesis and Pseudomonas aeruginosa showed high amylase activity.
Conclusion: Rhamnolipids could be used as a potential anti-microbial agent for treatment of infections.
     
Type of Study: Research | Subject: Microbiology
Received: 2020/09/14 | Accepted: 2021/02/22 | Published: 2021/02/22

Add your comments about this article : Your username or Email:
CAPTCHA

© 2021 All Rights Reserved | Research in Molecular Medicine

Designed & Developed by : Yektaweb