Research in Molecular Medicine
Research in Molecular Medicine
Res Mol Med (RMM)
Medical Sciences
http://rmm.mazums.ac.ir
1
admin
2322-1348
2322-133X
10.29252/rmm
en
jalali
1401
2
1
gregorian
2022
5
1
10
2
online
1
fulltext
en
Resistance Training May Improve Rectus Femoris Muscle Parameters in Elderly Women
فيزيولوژي
Phisiology
پژوهشي
Research
<div style="text-align: justify;"><span style="font-size:11pt"><span style="line-height:107%"><span calibri="" style="font-family:"><b><span style="font-size:12.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times="">Introduction:</span></span></span></b><span style="font-size:12.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""> One of the important issues in aging is sarcopenia characterized by muscle mass and function reduction. The present study investigated the effect of high intensity interval resistance training (HIIRT) on muscular parameters in sarcopenic elderly women.</span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:107%"><span calibri="" style="font-family:"><b><span style="font-size:12.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times="">Methods:</span></span></span></b><span style="font-size:12.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""> A total of 30 sarcopenic women aged 60 to 70 years (appendicular skeletal muscle mass index<6.76 kg/m2, hand grip<20 kg) were randomly assigned to the experimental (n=15) and control (n=15) groups. The experimental group (EX) participated in the training protocol that was implemented in 2 phases, the first phase (2 weeks/3 times per week/50-55% 1RM) and the second phase (6 weeks/3 times per week/60- 85% 1RM). The control group (C) did not participate in any training program during this period and performed their normal daily activities. Rectus femoris cross-sectional area (RFCSA), Myostatin (MSTN) to Insulin-like growth factor-1 (IGF-1), and MSTN to RF CSA were evaluated in two stages: pre-test (week 0) and post-test (end of week 8) and compared between groups. Independent t test and within groups one-way analysis of variance were subsequently utilized to assess the research variables through SPSS software version 23 at 0.05 level of significance.</span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:107%"><span calibri="" style="font-family:"><b><span style="font-size:12.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times="">Results:</span></span></span></b><span style="font-size:12.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""> The results showed that body mass (P=0.0001), body mass index (P=0.0001), MSTN to RF CSA (P=0.0001), and MSTN to IGF-1(P=0.04) decreased significantly in the EX group compared to the C group. While ASMI (P=0.0001), handgrip (P=0.0001), RF CSA (P=0.0001), and walking speed (P=0.0001) significantly increased.</span></span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:107%"><span calibri="" style="font-family:"><b><span style="font-size:12.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times="">Conclusion:</span></span></span></b><span style="font-size:12.0pt"><span style="line-height:107%"><span new="" roman="" style="font-family:" times=""> It seems that the HIIRT protocol resulted in an improvement in muscular parameters in sarcopenic elderly women. Based on our results, this type of training is safe and risk-free for the elderly and prevents the progressive reduction of muscle mass and strength. However, determining the exact mechanisms involved in these changes in response to HIIRT requires further molecular-cellular studies.</span></span></span></span></span></span><span style="font-size:11pt"><span style="line-height:107%"><span calibri="" style="font-family:"><span dir="RTL" style="font-family:"Arial","sans-serif"" lang="AR-SA"></span></span></span></span></div>
Keywords: High Intensity Interval Training, Cross Sectional Area, Aging, Sarcopenia, Hypertrophy
97
104
http://rmm.mazums.ac.ir/browse.php?a_code=A-10-672-1&slc_lang=en&sid=1
Zeinab
Hooshmandi
z_hooshmandi@pnu.ac.ir
100319475328460011332
100319475328460011332
Yes
Department of Exercise Physiology ,Payame Noor university,Tehran,Iran.
Farhad
Daryanoosh
daryanoosh@shirazu.ac.ir
100319475328460011333
100319475328460011333
No
Department of Sport Sciences, Shiraz University, Shiraz, Iran
Pegah
Jahani
pegah.jahanii@gmail.com
100319475328460011334
100319475328460011334
No
Radiology resident, Department of Radiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.