en بیوتکنولوژی Biotechnology review review <div style="text-align: justify;"><span style="font-size:11pt"><span style="line-height:150%"><span calibri="" style="font-family:"><span style="font-size:12.0pt"><span style="line-height:150%"><span new="" roman="" style="font-family:" times="">Recently, the market demand for biopharmaceuticals and nutraceuticals has increased. Consequently, high-volume production strategies have also drawn a lot of attention. The invention and development of recombinant DNA technology, using various hosts from bacteria to mammalian cells, have led to the industrial-scale manufacture of many valuable pharmaceutical products. Among the hosts, yeasts have a special place due to their numerous benefits. The present study deals with commercial yeast-derived biopharmaceuticals and laboratory-scale yeast-extracted nutraceuticals. It represents the biotechnological potential of yeasts to meet the market&#39;s needs in this area. Besides, considering the COVID-19 pandemic, the applications of yeast hosts for the clinical management of this disease have been briefly discussed.</span></span></span></span></span></span></div> Biologicals, Biopharmaceuticals, COVID-19, Nutraceuticals, Yeast 65 84 http://rmm.mazums.ac.ir/browse.php?a_code=A-10-1246-1&slc_lang=en&sid=1 Farzane Arianfar arianfar.farzane@gmail.com 100319475328460011326 100319475328460011326 No Department of Medical Biotechnology, Faculty of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran Parastoo Tarighi tarighi.p@iums.ac.ir 100319475328460011327 100319475328460011327 No Department of Medical Biotechnology, Faculty of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran Marjan Shariatpanahi shariatpanahi.m@iums.ac.ir 100319475328460011328 100319475328460011328 No Department of Pharmacology and Toxicology, School of Pharmacy, Iran University of Medical Sciences, Tehran, Iran Seyedeh Mona Mousavi Esfahani 100319475328460011329 100319475328460011329 No Department of Medical Biotechnology, Faculty of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran Negar Mottaghi-Dastjerdi Mottaghi.n@iums.ac.ir 100319475328460011330 100319475328460011330 Yes Department of Pharmacognosy and Pharmaceutical Biotechnology, School of Pharmacy, Iran University of Medical Sciences, Tehran, Iran