en ايمونولوژي Immunology پژوهشي Research <div style="text-align: justify;"><strong>Background:</strong> Despite close monitoring of transplant patients, Cytomegalovirus (CMV) infection has remained one of the most critical problems in transplantation. This study investigates the relationship between CMV viral load and clinical laboratory findings in transplant recipients.</div> <div style="text-align: justify;"><strong>Materials And Methods:</strong> A total of 34 transplant recipients comprising 15 Kidney Transplant (KT) recipients and 19 Bone Marrow Transplant (BMT) recipients admitted to the Imam Reza Hospital in Kermanshah Province, Iran, were enrolled in this study. The CMV viral load was quantified by the real-time PCR technique.</div> <div style="text-align: justify;"><strong>Results:</strong> The CMV viral load in KT recipients was significantly higher than in BMT recipients (P=0.03), and there was a positive association between the level of virus and the level of cyclosporine in the blood of patients (r=0.51, P=0.02). Besides, CMV viral load was positively correlated with WBC (r=0.32, P=0.04), urea (r=0.47, P=0.002), creatinine (r=0.39, P=0.01), aspartate aminotransferase (r=0.33, P=0.04), and lactate dehydrogenase (r=0.4, P=0.01). Also, it was negatively associated with albumin (r=-0.61, P<0.001), sodium (r=-0.4, P=0.01), and calcium levels (r=-0.46, P=0.003). There were also significant differences between KT and BMT recipients regarding the CMV-related clinical laboratory findings of urea (P=0.02), creatinine (P=0.001), uric acid (P=0.005), direct bilirubin (P=0.04), albumin (P=0.04), platelet (P<0.001), and sodium (P=0.04) levels.</div> <div style="text-align: justify;"><strong>Conclusion:</strong> Based on present data, we conclude that despite careful monitoring of patients, infection with CMV is still one of the most important problems associated with organ transplantation, which is directly related to many laboratory findings.</div> Cytomegalovirus, Bone marrow transplantation, Kidney transplantation, Viral load, Cyclosporine 197 208 http://rmm.mazums.ac.ir/browse.php?a_code=A-10-1222-1&slc_lang=en&sid=1 Misagh Rajabinejad misagh.ra@gmail.com 100319475328460010890 100319475328460010890 No Student Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Ramin Lotfi ramin.lotfi1370@gmail.com 100319475328460010891 100319475328460010891 No Clinical Research Development Center, Tohid Hospital, Kurdistan University of Medical Sciences, Sanandaj, Iran Seyed Askar Roghani askar.roghani@gmail.com 100319475328460010892 100319475328460010892 Yes Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran Elham Koolani d.k.777.a@gmail.com 100319475328460010893 100319475328460010893 No Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran Bijan Soleymani bijan.soleymani@kums.ac.ir 100319475328460010894 100319475328460010894 No Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran Alireza Rezaiemanesh alirezarezaeimanesh@gmail.com 100319475328460010895 100319475328460010895 No Department of Immunology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran Zahra Mohamadi Kish zahra.mohamadikish26@gmail.com 100319475328460010896 100319475328460010896 No Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran Behrooz Halashi immuno_halashi@yahoo.com 100319475328460010897 100319475328460010897 No Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran Ali Khorasanizadeh alikhorasanizadeh71@gmail.com 100319475328460010898 100319475328460010898 No Student Research Committee, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Zhila Shaveisizadeh zh.shaveisizadeh@gmail.com 100319475328460010899 100319475328460010899 No Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran Kamran Mansouri kamranmansouri@gmail.com 100319475328460010900 100319475328460010900 No Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran