en بیهوشی Anesthesia پژوهشي Research <p dir="ltr" style="text-align: justify"><strong>&nbsp;Background: </strong>Calcium (Ca⁺²) plays an important role in many biophysiological mechanisms .The present study was carried out to assess alterations in total serum calcium level before and after operations in consider to the type of anesthesia.</p> <p dir="ltr" style="text-align: justify"><strong>Materials and Methods:</strong> This descriptive study was conducted on 74 women who candidate for gynecological abdominal operations during one year at Al-zahra maternity Hospital in Rasht, Iran. The patients underwent General Anesthesia (GA) (N=37) or Spinal Anesthesia (SA) (N=37) randomly. Blood samples (2 cc), were obtained an hour before the anesthesia and two hours after that. The blood samples had been sent to the laboratory for analyzing .Total serum calcium level, magnesium (Mg) and albumin level were measured by photometric methods. Inferential statistic was analyzed with the Vilkson non-parametric and Pearson&#39;s correlation test. P-values less than 0.05 have been considered as significant different.</p> <p dir="ltr" style="text-align: justify"><strong>Results: </strong>There was a significant trend to decrease in calcium levels after all gynecological abdominal operations, but there was a significant correlation between General anesthesia (GA) and reduction of serum calcium level (p=0.026) . Therefore, General Anesthesia (GA) is accompanied by more calcium reduction than Spinal Anesthesia (SA).</p> <p dir="ltr" style="text-align: justify"><strong>Conclusion: </strong>Serum Calcium levels tend to decrease after all gynecological abdominal surgeries, but General Anesthesia (GA) is accompanied by more calcium reduction than Spinal one. It needs to further specific studies, to illustrate association between different methods of anesthesia and Ca⁺² changes.</p> Calcium (Ca), Hypocalcaemia, Gynecologic Surgeries, General Anesthesia (GA), Spinal Anesthesia (SA), ASA (American Society of Anesthesiologists) 41 46 http://rmm.mazums.ac.ir/browse.php?a_code=A-10-649-2&slc_lang=en&sid=1 Katayoun Haryalchi 10031947532846006237 10031947532846006237 No Department of Anesthesiology ,Reproductive Health Research Center, Guilan University of Medical Sciences, Rasht, Iran Yasaman Yaghoubi yasamanyaghobi@yahoo.com 10031947532846006238 10031947532846006238 Yes Department, Langroud Nursing and Midwifery School, Guilan University of Medical Sciences, Rasht, Neda Habibi Arejan 10031947532846006239 10031947532846006239 No Department of Internal Medicine, Metabolic Disease Research Center, Qazvin University of Medical Science, Qazvin, Iran. Leila Farhadi 10031947532846006240 10031947532846006240 No Faculty of Microbiology, Tehran University, Tehran, Iran Zahra Hosseini khah 10031947532846006241 10031947532846006241 No School of Advanced Medical Technologies, Tehran University of Medical Science, Tehran, Iran.