Volume 14, Issue 2 (May 2026)
Res Mol Med (RMM) 2026, 14(2): 0-0 |
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Zamani Hajiabadi I, Niknam M M, Samadaeegelehkolaee K. Influenza A-Induced Rhabdomyolysis Without Acute Kidney Injury: A Case Report. Res Mol Med (RMM) 2026; 14 (2)
URL: http://rmm.mazums.ac.ir/article-1-645-en.html
URL: http://rmm.mazums.ac.ir/article-1-645-en.html
1- Department of Internal Medicine, Semnan University of Medical Sciences, Semnan, Iran.
2- Student Research Committee, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
3- Sexual and Reproductive Health Research Center, Department of Reproductive Health and Midwifery, Faculty of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, Iran. ,k-samadaee@alumnus.tums.ac.ir
2- Student Research Committee, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
3- Sexual and Reproductive Health Research Center, Department of Reproductive Health and Midwifery, Faculty of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, Iran. ,
Abstract: (27 Views)
Background: Rhabdomyolysis is a clinical syndrome characterized by the breakdown of muscle cells and release of intracellular contents into the bloodstream. Viral infections, including influenza A, are rare but important causes.
Case Presentation: A 27-year-old healthy male presented with fever and weakness. His creatine kinase (CK) level was 19,000 U/L, and CK-myocardial band (CK-MB) was 2,636 U/L. He tested positive for H1N1 by polymerase chain reaction. Despite severe rhabdomyolysis, he did not develop acute kidney injury (AKI).
Results: The patient received intravenous fluids (1-liter bolus, then 4 liters/day for 5 days). CK levels decreased to 2,500 U/L by day 5. Echocardiography was normal.
Conclusion: Influenza-induced rhabdomyolysis can occur without acute kidney injury (AKI), even with CK >19,000 U/L. Early fluid resuscitation may prevent renal injury.
Case Presentation: A 27-year-old healthy male presented with fever and weakness. His creatine kinase (CK) level was 19,000 U/L, and CK-myocardial band (CK-MB) was 2,636 U/L. He tested positive for H1N1 by polymerase chain reaction. Despite severe rhabdomyolysis, he did not develop acute kidney injury (AKI).
Results: The patient received intravenous fluids (1-liter bolus, then 4 liters/day for 5 days). CK levels decreased to 2,500 U/L by day 5. Echocardiography was normal.
Conclusion: Influenza-induced rhabdomyolysis can occur without acute kidney injury (AKI), even with CK >19,000 U/L. Early fluid resuscitation may prevent renal injury.
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