دوره 1، شماره 1 - ( بهار 1391 )                   جلد 1 شماره 1 صفحات 40-42 | برگشت به فهرست نسخه ها




DOI: 10.18869/acadpub.rmm.1.1.40

XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Hashemi A, Abediankenari S, Madani A. Alterations in salivary IgA levels in infectious and inflammatory disorders of upper respiratory tract. Res Mol Med (RMM). 2013; 1 (1) :40-42
URL: http://rmm.mazums.ac.ir/article-1-28-fa.html
Alterations in salivary IgA levels in infectious and inflammatory disorders of upper respiratory tract. Research in Molecular Medicine. 1391; 1 (1) :40-42

URL: http://rmm.mazums.ac.ir/article-1-28-fa.html


چکیده:   (5677 مشاهده)

Background: The airway surfaces are one of the most common ways of entry of infectious agents. Oral cavity associated lymphoid tissues are inductive site of humoral immune responses in inflammatory and infectious disorders of the upper respiratory tract. These lymphoid tissues play important roles in the induction of salivary IgA. The impact of upper respiratory tract diseases on salivary IgA production has not been fully understood. Therefore, in this study, we investigated the salivary IgA levels in patients suffered from upper respiratory tract diseases to indicate the effect of these diseases on salivary IgA production.
Materials and Methods: In this study, salivary IgA level of 156 patients with inflammatory diseases of the upper respiratory tract including chronic rhinosinusitis, ear and pharynx diseases have been evaluated by direct immunoenzymatic determination.
Results: In pharynx disorders 11.8 % of patients were IgA deficient , 76.2 % were normal and11.8 % had elevated level of IgA .In patients with chronic rhinosinusitis IgA deficiency was observed in 9.2 % , 75.9 % were normal and there was an elevation in 14.8 % of patients .In ear disorders 11.6% were IgA deficient ,76.7 % normal and 11.6 % had elevated IgA level.
Conclusion: This study provided evidence for the first time that changes in salivary IgA level are almost the same in different sites of infectious and inflammatory diseases of upper respiratory tract. Our investigation revealed that local up regulation of salivary IgA is not particular interest in majority of patients with upper respiratory tract infections.

متن کامل [PDF 358 kb]   (1129 دریافت)    
نوع مطالعه: پژوهشي | موضوع مقاله: ايمونولوژي
دریافت: ۱۳۹۱/۱۱/۱۸ | پذیرش: ۱۳۹۲/۵/۲۰ | انتشار: ۱۳۹۲/۵/۲۰

ارسال نظر درباره این مقاله : نام کاربری یا پست الکترونیک شما:
کد امنیتی را در کادر بنویسید

کلیه حقوق این وب سایت متعلق به Research in Molecular Medicine می باشد.

طراحی و برنامه نویسی : یکتاوب افزار شرق

© 2015 All Rights Reserved | Research in Molecular Medicine

Designed & Developed by : Yektaweb