دوره 3، شماره 1 - ( زمستان 1393 )                   جلد 3 شماره 1 صفحات 1-5 | برگشت به فهرست نسخه ها



DOI: 10.7508/rmm.2015.01.001

XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Nazm-Bbojnordi M, Ghasemi Hamidabadi H. Spermatogonia stem cells: A new pluripotent source for repairment in regenerative medicine. Res Mol Med (RMM). 2015; 3 (1) :1-5
URL: http://rmm.mazums.ac.ir/article-1-108-fa.html
Spermatogonia stem cells: A new pluripotent source for repairment in regenerative medicine. Research in Molecular Medicine. 1393; 3 (1) :1-5

URL: http://rmm.mazums.ac.ir/article-1-108-fa.html


چکیده:   (2452 مشاهده)

Recently new reports have proved the pluripotency of spermatogonial stem cells (SSCs) derived from male gonad. This pluripotent stem cells resembled Embryonic stem cells recognized as Embryonic Stem like cells (ES like cells). ES like cells forms sharp edge colonies that are immunopositive to pluripotency markers and have differentiation capacity to Ectodermal, Mesodermal and Endodermal layers. ES like cells may have therapeutique application in tissue engineering and treatment for disease because of their ability to differentiation into various cell types. Embryonic stem like cells derived culturing of spermatogonial cells which has self-renewal and differentiation capacity to all three germ layers make them as a new and unlimited source for cell therapy strategies. The perspective of pluripotency and differantiaion ability of ES like cells obtained in mice has clinical application in other species particularly in humans that solves many problems of cell therapy in regenerative medicine. These characteristics propose the therapeutic use of spermatogonial stem cells as a possible alternative source for generation of various cell types that are usful in treatment of degenerative diseases.

متن کامل [PDF 370 kb]   (812 دریافت)    
نوع مطالعه: review | موضوع مقاله: بيولوژي
دریافت: ۱۳۹۳/۹/۵ | پذیرش: ۱۳۹۳/۱۲/۸ | انتشار: ۱۳۹۳/۱۲/۸

ارسال نظر درباره این مقاله : نام کاربری یا پست الکترونیک شما:
کد امنیتی را در کادر بنویسید

کلیه حقوق این وب سایت متعلق به Research in Molecular Medicine می باشد.

طراحی و برنامه نویسی : یکتاوب افزار شرق

© 2015 All Rights Reserved | Research in Molecular Medicine

Designed & Developed by : Yektaweb